Lois was Timothy's grandmother, remembered by Paul for the sincere faith that also lived in Timothy's mother Eunice and in Timothy.
Biography
Second Timothy 1:5 names Lois as the first person in Timothy's family whom Paul mentions as possessing sincere faith, followed by Eunice and Timothy. Later in the letter Paul recalls Timothy's knowledge of the sacred writings from childhood, consistent with the influence of this faithful family. Scripture provides no further biography of Lois.
Biblical Significance
Lois is a notable New Testament example of intergenerational faith. Her brief mention honors the formative influence of family members who transmit knowledge of Scripture and genuine trust in God.